You must have completed the Druidic Ritual Quest in order to begin using this skill. To start this quest speaks to Kaqemeex who is located at the Druids' circle, north of Taverley.
There are three main ways in which you can obtain herbs within RuneScape. There are advantages to each style; more practiced herbalists can use a combination of techniques in order to achieve maximum levels of stock.
You can obtain herbs through:
Farming
Through the use of the Farming skill, you can choose which herbs you want to grow (once the necessary seeds have been obtained, of course). Those who use this skill proficiently will be able to grow crops, as well as herbs and many other plants.
Drops
Many monsters and other NPCs can be killed for herb drops. Herbs obtained in this manner will be grimy and will need to be cleaned in order to use them. Monsters that drop grimy herbs include:
Men and women
Thugs
Skeletons
Chaos druids
Slayer monsters, especially cave crawlers.
Purchase
The richer herbalists may buy herbs from people who have gathered stock using the above two methods. A lot of the herbs you find within the game will be grimy. To be able to use them you will first need to use your Herblore skill to clean them. To clean an herb, simply click on it with the left mouse button (or right-click on it and choose 'Clean' from the list of options).
If you have the appropriate Herblore level needed to clean the herb, it will be ready to be used in making potions. As your Herblore level increases so will your ability to clean different types of herbs.
Creating Potions and Poisons
Some higher level creations will use coconut milk instead of water. Coconut milk is made by using a hammer on a coconut, which can be picked from a palm tree.
The same type potion can also be combined. For example, if you have a 1 dose and a 3 dose attack potion, you can right-click and 'use' one of the potions on the other, making a 4 dose potion. Alternatively, choose to empty the vial by using the right-click option.
Now that you know what all the ingredients are and how to put them together in order to create a potion, you are ready to begin mastering the Herblore skill. The easiest way in which to advance your Herblore is to actually make potions and poisons.
Sinister Chest
In the Yanille Agility Dungeon resides Salarin the Twisted. He can only be defeated by elemental strike spells but, if you are successful, there is a chance that he may drop a sinister key, which is used to open the sinister chest in the skeleton room.
Upon opening the chest you will get poisoned, so it is a good idea to bring along an anti-poison of some type.
The chest contains a fixed set of nine cleaned herbs, which are:
2 x harralander
3 x ranarr
1 x irit
1 x avantoe
1 x kwuarm
1 x torstol
Herb Gloves
There are a few sets of gloves available from the Fist of Guthix mini-game that anyone interested in Herblore should look to purchase. Irit, avantoe, kwuarm and cadantine gloves increase the chance that you will receive those herbs as drops instead of other herbs. Any time that you would receive a herb drop, there is a 50% chance that it will automatically be the same herb as your gloves. This has no effect on creatures like fever spiders, who only drop one type of herb. These gloves will crumble to dust after 100 drops of the same herb as your gloves.

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